Childhood tuberculosis: out of sight, out of mind?
Despite significant improvements in tuberculosis (TB) management under the WHO directly observed treatment, short course (DOTS) strategy, childhood TB has been relatively neglected. Children are at high risk of severe disease, and reactivation of latent infection in adulthood perpetuates the epidemi...
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655359/ https://www.ncbi.nlm.nih.gov/pubmed/17996915 http://dx.doi.org/10.1016/j.trstmh.2007.09.011 |
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author | Brent, Andrew J. Anderson, Suzanne T. Kampmann, Beate |
author_facet | Brent, Andrew J. Anderson, Suzanne T. Kampmann, Beate |
author_sort | Brent, Andrew J. |
collection | PubMed |
description | Despite significant improvements in tuberculosis (TB) management under the WHO directly observed treatment, short course (DOTS) strategy, childhood TB has been relatively neglected. Children are at high risk of severe disease, and reactivation of latent infection in adulthood perpetuates the epidemic. Almost a million cases of childhood TB are estimated to occur annually, but good-quality epidemiological data are scarce due to inherent difficulties diagnosing paediatric TB. There remains an urgent need both for better diagnostic tests and for robust regional data on the true burden of disease, otherwise childhood TB will remain an essentially ‘invisible’ and therefore neglected disease. |
format | Text |
id | pubmed-2655359 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-26553592009-03-15 Childhood tuberculosis: out of sight, out of mind? Brent, Andrew J. Anderson, Suzanne T. Kampmann, Beate Trans R Soc Trop Med Hyg Mini-Review Despite significant improvements in tuberculosis (TB) management under the WHO directly observed treatment, short course (DOTS) strategy, childhood TB has been relatively neglected. Children are at high risk of severe disease, and reactivation of latent infection in adulthood perpetuates the epidemic. Almost a million cases of childhood TB are estimated to occur annually, but good-quality epidemiological data are scarce due to inherent difficulties diagnosing paediatric TB. There remains an urgent need both for better diagnostic tests and for robust regional data on the true burden of disease, otherwise childhood TB will remain an essentially ‘invisible’ and therefore neglected disease. Oxford University Press 2008-03 /pmc/articles/PMC2655359/ /pubmed/17996915 http://dx.doi.org/10.1016/j.trstmh.2007.09.011 Text en © 2008 Elsevier Ltd. https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use. |
spellingShingle | Mini-Review Brent, Andrew J. Anderson, Suzanne T. Kampmann, Beate Childhood tuberculosis: out of sight, out of mind? |
title | Childhood tuberculosis: out of sight, out of mind? |
title_full | Childhood tuberculosis: out of sight, out of mind? |
title_fullStr | Childhood tuberculosis: out of sight, out of mind? |
title_full_unstemmed | Childhood tuberculosis: out of sight, out of mind? |
title_short | Childhood tuberculosis: out of sight, out of mind? |
title_sort | childhood tuberculosis: out of sight, out of mind? |
topic | Mini-Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655359/ https://www.ncbi.nlm.nih.gov/pubmed/17996915 http://dx.doi.org/10.1016/j.trstmh.2007.09.011 |
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