Childhood tuberculosis: out of sight, out of mind?

Despite significant improvements in tuberculosis (TB) management under the WHO directly observed treatment, short course (DOTS) strategy, childhood TB has been relatively neglected. Children are at high risk of severe disease, and reactivation of latent infection in adulthood perpetuates the epidemi...

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Autores principales: Brent, Andrew J., Anderson, Suzanne T., Kampmann, Beate
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655359/
https://www.ncbi.nlm.nih.gov/pubmed/17996915
http://dx.doi.org/10.1016/j.trstmh.2007.09.011
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author Brent, Andrew J.
Anderson, Suzanne T.
Kampmann, Beate
author_facet Brent, Andrew J.
Anderson, Suzanne T.
Kampmann, Beate
author_sort Brent, Andrew J.
collection PubMed
description Despite significant improvements in tuberculosis (TB) management under the WHO directly observed treatment, short course (DOTS) strategy, childhood TB has been relatively neglected. Children are at high risk of severe disease, and reactivation of latent infection in adulthood perpetuates the epidemic. Almost a million cases of childhood TB are estimated to occur annually, but good-quality epidemiological data are scarce due to inherent difficulties diagnosing paediatric TB. There remains an urgent need both for better diagnostic tests and for robust regional data on the true burden of disease, otherwise childhood TB will remain an essentially ‘invisible’ and therefore neglected disease.
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spelling pubmed-26553592009-03-15 Childhood tuberculosis: out of sight, out of mind? Brent, Andrew J. Anderson, Suzanne T. Kampmann, Beate Trans R Soc Trop Med Hyg Mini-Review Despite significant improvements in tuberculosis (TB) management under the WHO directly observed treatment, short course (DOTS) strategy, childhood TB has been relatively neglected. Children are at high risk of severe disease, and reactivation of latent infection in adulthood perpetuates the epidemic. Almost a million cases of childhood TB are estimated to occur annually, but good-quality epidemiological data are scarce due to inherent difficulties diagnosing paediatric TB. There remains an urgent need both for better diagnostic tests and for robust regional data on the true burden of disease, otherwise childhood TB will remain an essentially ‘invisible’ and therefore neglected disease. Oxford University Press 2008-03 /pmc/articles/PMC2655359/ /pubmed/17996915 http://dx.doi.org/10.1016/j.trstmh.2007.09.011 Text en © 2008 Elsevier Ltd. https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use.
spellingShingle Mini-Review
Brent, Andrew J.
Anderson, Suzanne T.
Kampmann, Beate
Childhood tuberculosis: out of sight, out of mind?
title Childhood tuberculosis: out of sight, out of mind?
title_full Childhood tuberculosis: out of sight, out of mind?
title_fullStr Childhood tuberculosis: out of sight, out of mind?
title_full_unstemmed Childhood tuberculosis: out of sight, out of mind?
title_short Childhood tuberculosis: out of sight, out of mind?
title_sort childhood tuberculosis: out of sight, out of mind?
topic Mini-Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655359/
https://www.ncbi.nlm.nih.gov/pubmed/17996915
http://dx.doi.org/10.1016/j.trstmh.2007.09.011
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