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The increase in pulmonary arterial pressure caused by hypoxia depends on iron status

Hypoxia is a major cause of pulmonary hypertension. Gene expression activated by the transcription factor hypoxia-inducible factor (HIF) is central to this process. The oxygen-sensing iron-dependent dioxygenase enzymes that regulate HIF are highly sensitive to varying iron availability. It is unknow...

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Detalles Bibliográficos
Autores principales:	Smith, Thomas G, Balanos, George M, Croft, Quentin P P, Talbot, Nick P, Dorrington, Keith L, Ratcliffe, Peter J, Robbins, Peter A
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Science Inc 2008
Materias:	Respiratory
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655431/ https://www.ncbi.nlm.nih.gov/pubmed/18955380 http://dx.doi.org/10.1113/jphysiol.2008.160960

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