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Sperm from Hyh Mice Carrying a Point Mutation in αSNAP Have a Defect in Acrosome Reaction
Hydrocephalus with hop gait (hyh) is a recessive inheritable disease that arose spontaneously in a mouse strain. A missense mutation in the Napa gene that results in the substitution of a methionine for isoleucine at position 105 (M105I) of αSNAP has been detected in these animals. αSNAP is a ubiqui...
Autores principales: | Bátiz, Luis Federico, De Blas, Gerardo A., Michaut, Marcela A., Ramírez, Alfredo R., Rodríguez, Facundo, Ratto, Marcelo H., Oliver, Cristian, Tomes, Claudia N., Rodríguez, Esteban M., Mayorga, Luis S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655651/ https://www.ncbi.nlm.nih.gov/pubmed/19305511 http://dx.doi.org/10.1371/journal.pone.0004963 |
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