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A self-cleaving DNA enzyme modified with amines, guanidines and imidazoles operates independently of divalent metal cations (M(2+))
The selection of modified DNAzymes represents an important endeavor in expanding the chemical and catalytic properties of catalytic nucleic acids. Few examples of such exist and to date, there is no example where three different modified bases have been simultaneously incorporated for catalytic acti...
Autores principales: | Hollenstein, Marcel, Hipolito, Christopher J., Lam, Curtis H., Perrin, David M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655665/ https://www.ncbi.nlm.nih.gov/pubmed/19153138 http://dx.doi.org/10.1093/nar/gkn1070 |
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