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Histone H3 Lys79 methylation is required for efficient nucleotide excision repair in a silenced locus of Saccharomyces cerevisiae
Methylation of specific histone lysine residues regulates gene expression and heterochromatin function, but little is known about its role in DNA repair. To examine how changes in conserved methylated residues of histone H3 affect nucleotide excision repair (NER), viable H3K4R and H3K79R mutants wer...
Autores principales: | Chaudhuri, Shubho, Wyrick, John J., Smerdon, Michael J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655692/ https://www.ncbi.nlm.nih.gov/pubmed/19155276 http://dx.doi.org/10.1093/nar/gkp003 |
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