Unconventional decoding of the AUA codon as methionine by mitochondrial tRNA(Met) with the anticodon f(5)CAU as revealed with a mitochondrial in vitro translation system

Mitochondrial (mt) tRNA(Met) has the unusual modified nucleotide 5-formylcytidine (f(5)C) in the first position of the anticodon. This tRNA must translate both AUG and AUA as methionine. By constructing an in vitro translation system from bovine liver mitochondria, we examined the decoding propertie...

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Detalles Bibliográficos
Autores principales: Takemoto, Chie, Spremulli, Linda L., Benkowski, Lisa A., Ueda, Takuya, Yokogawa, Takashi, Watanabe, Kimitsuna
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655697/
https://www.ncbi.nlm.nih.gov/pubmed/19151083
http://dx.doi.org/10.1093/nar/gkp001

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