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C5a Enhances Dysregulated Inflammatory and Angiogenic Responses to Malaria In Vitro: Potential Implications for Placental Malaria

BACKGROUND: Placental malaria (PM) is a leading cause of maternal and infant mortality. Although the accumulation of parasitized erythrocytes (PEs) and monocytes within the placenta is thought to contribute to the pathophysiology of PM, the molecular mechanisms underlying PM remain unclear. Based on...

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Detalles Bibliográficos
Autores principales:	Conroy, Andrea, Serghides, Lena, Finney, Constance, Owino, Simon O., Kumar, Sanjeev, Gowda, D. Channe, Liles, W. Conrad, Moore, Julie M., Kain, Kevin C.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655724/ https://www.ncbi.nlm.nih.gov/pubmed/19308263 http://dx.doi.org/10.1371/journal.pone.0004953

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