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Epitope spreading in animal models: array of hope in rheumatoid arthritis and multiple sclerosis
The paradigm for pathogenic autoimmunity is the generation of high-titre, affinity-matured autoantibodies to a restricted family of autoantigens, in the appropriate genetic context. Genetic determinants of autoimmunity are largely found within the major histocompatibility complex (MHC) and the '...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656229/ https://www.ncbi.nlm.nih.gov/pubmed/19090965 http://dx.doi.org/10.1186/ar2544 |