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Arthritogenic T cell epitope in glucose-6-phosphate isomerase-induced arthritis
INTRODUCTION: Arthritis induced by immunisation with glucose-6-phosphate isomerase (GPI) in DBA/1 mice was proven to be T helper (Th) 17 dependent. We undertook this study to identify GPI-specific T cell epitopes in DBA/1 mice (H-2q) and investigate the mechanisms of arthritis generation. METHODS: F...
Autores principales: | Iwanami, Keiichi, Matsumoto, Isao, Tanaka, Yoko, Inoue, Asuka, Goto, Daisuke, Ito, Satoshi, Tsutsumi, Akito, Sumida, Takayuki |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656230/ https://www.ncbi.nlm.nih.gov/pubmed/18992137 http://dx.doi.org/10.1186/ar2545 |
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