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Cartilage oligomeric matrix protein deficiency promotes early onset and the chronic development of collagen-induced arthritis
INTRODUCTION: Cartilage oligomeric matrix protein (COMP) is a homopentameric protein in cartilage. The development of arthritis, like collagen-induced arthritis (CIA), involves cartilage as a target tissue. We have investigated the development of CIA in COMP-deficient mice. METHODS: COMP-deficient m...
Autores principales: | Geng, Hui, Carlsen, Stefan, Nandakumar, Kutty Selva, Holmdahl, Rikard, Aspberg, Anders, Oldberg, Åke, Mattsson, Ragnar |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656236/ https://www.ncbi.nlm.nih.gov/pubmed/19014566 http://dx.doi.org/10.1186/ar2551 |
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