Collagen-specific T-cell repertoire in blood and synovial fluid varies with disease activity in early rheumatoid arthritis

INTRODUCTION: Type II collagen is a DR4/DR1 restricted target of self-reactive T cells that sustain rheumatoid arthritis. The aim of the present study was to analyze the T-cell receptor repertoire at the onset of and at different phases in rheumatoid arthritis. METHODS: We used the CDR3 BV-BJ spectr...

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Detalles Bibliográficos
Autores principales: Ria, Francesco, Penitente, Romina, De Santis, Maria, Nicolò, Chiara, Di Sante, Gabriele, Orsini, Massimiliano, Arzani, Dario, Fattorossi, Andrea, Battaglia, Alessandra, Ferraccioli, Gian Franco
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656238/
https://www.ncbi.nlm.nih.gov/pubmed/19014626
http://dx.doi.org/10.1186/ar2553

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