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Retinoid X receptor and peroxisome proliferator-activated receptor-gamma agonists cooperate to inhibit matrix metalloproteinase gene expression

INTRODUCTION: We recently described the ability of retinoid X receptor (RXR) ligand LG100268 (LG268) to inhibit interleukin-1-beta (IL-1-β)-driven matrix metalloproteinase-1 (MMP-1) and MMP-13 gene expression in SW-1353 chondrosarcoma cells. Other investigators have demonstrated similar effects in c...

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Detalles Bibliográficos
Autores principales:	Burrage, Peter S, Schmucker, Adam C, Ren, Yanqing, Sporn, Michael B, Brinckerhoff, Constance E
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656243/ https://www.ncbi.nlm.nih.gov/pubmed/19046432 http://dx.doi.org/10.1186/ar2564

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