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Improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis

We report a case of acute demyelinating encephalitis that occurred after viral vaccination against hepatitis A-, hepatitis B-, and poliovirus and vaccination against bacterial toxins of diphtheria and tetanus. After different diagnosis had been excluded, we diagnosed postvaccinal demyelinating encep...

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Autores principales: Rogalewski, Andreas, Kraus, Jörg, Hasselblatt, Martin, Kraemer, Christoffer, Schäbitz, Wolf-Rüdiger
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656344/
https://www.ncbi.nlm.nih.gov/pubmed/19300637
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author Rogalewski, Andreas
Kraus, Jörg
Hasselblatt, Martin
Kraemer, Christoffer
Schäbitz, Wolf-Rüdiger
author_facet Rogalewski, Andreas
Kraus, Jörg
Hasselblatt, Martin
Kraemer, Christoffer
Schäbitz, Wolf-Rüdiger
author_sort Rogalewski, Andreas
collection PubMed
description We report a case of acute demyelinating encephalitis that occurred after viral vaccination against hepatitis A-, hepatitis B-, and poliovirus and vaccination against bacterial toxins of diphtheria and tetanus. After different diagnosis had been excluded, we diagnosed postvaccinal demyelinating encephalitis and started treatment with high dose intravenous methylprednisolone, followed by peroral application in decreasing dosages for three weeks. A few days after the treatment with methylprednisolone had been finished, the patient’s medical condition deteriorated again. Thus, we initiated plasma exchange at an advanced state of illness, which led to significant continuous improvement. The role of plasma exchange is discussed controversially, in particular the issue of timing. We report a case that shows improvement due to plasmapheresis several weeks after symptom onset.
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spelling pubmed-26563442009-03-19 Improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis Rogalewski, Andreas Kraus, Jörg Hasselblatt, Martin Kraemer, Christoffer Schäbitz, Wolf-Rüdiger Neuropsychiatr Dis Treat Case Report We report a case of acute demyelinating encephalitis that occurred after viral vaccination against hepatitis A-, hepatitis B-, and poliovirus and vaccination against bacterial toxins of diphtheria and tetanus. After different diagnosis had been excluded, we diagnosed postvaccinal demyelinating encephalitis and started treatment with high dose intravenous methylprednisolone, followed by peroral application in decreasing dosages for three weeks. A few days after the treatment with methylprednisolone had been finished, the patient’s medical condition deteriorated again. Thus, we initiated plasma exchange at an advanced state of illness, which led to significant continuous improvement. The role of plasma exchange is discussed controversially, in particular the issue of timing. We report a case that shows improvement due to plasmapheresis several weeks after symptom onset. Dove Medical Press 2007-12 /pmc/articles/PMC2656344/ /pubmed/19300637 Text en © 2007 Dove Medical Press Limited. All rights reserved
spellingShingle Case Report
Rogalewski, Andreas
Kraus, Jörg
Hasselblatt, Martin
Kraemer, Christoffer
Schäbitz, Wolf-Rüdiger
Improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis
title Improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis
title_full Improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis
title_fullStr Improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis
title_full_unstemmed Improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis
title_short Improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis
title_sort improvement of advanced postvaccinal demyelinating encephalitis due to plasmapheresis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656344/
https://www.ncbi.nlm.nih.gov/pubmed/19300637
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