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Age of smoking initiation and risk of breast cancer in a sample of Ontario women
OBJECTIVES: To examine the association between time of smoking initiation and both the independent and joint effects of active and passive tobacco smoke exposure and the risk of breast cancer in a sample of Ontario women. METHODS: Data from two large population-based case-control studies conducted a...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656478/ https://www.ncbi.nlm.nih.gov/pubmed/19222858 http://dx.doi.org/10.1186/1617-9625-5-4 |
Sumario: | OBJECTIVES: To examine the association between time of smoking initiation and both the independent and joint effects of active and passive tobacco smoke exposure and the risk of breast cancer in a sample of Ontario women. METHODS: Data from two large population-based case-control studies conducted among Ontario women aged 25–75 years were combined for analysis (n = 12,768). RESULTS: Women who had ever smoked and were exposed to passive smoke had a significant increased risk of breast cancer (OR 1.13, 95%CI 1.01–1.25). A significant increased risk was also observed among women who initiated smoking: at age 26 or older (OR 1.26, 95%CI 1.03–1.55); more than five years from menarche (OR 1.26, 95%CI 1.12–1.42); and, after their first live birth (OR 1.25, 95%CI 1.02–1.52). CONCLUSION: The results suggest that women who initiate smoking at an older age are at an increased risk of breast cancer. |
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