MicroRNA-199b-5p Impairs Cancer Stem Cells through Negative Regulation of HES1 in Medulloblastoma

BACKGROUND: Through negative regulation of gene expression, microRNAs (miRNAs) can function in cancers as oncosuppressors, and they can show altered expression in various tumor types. Here we have investigated medulloblastoma tumors (MBs), which arise from an early impairment of developmental proces...

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Detalles Bibliográficos
Autores principales: Garzia, Livia, Andolfo, Immacolata, Cusanelli, Emilio, Marino, Natascia, Petrosino, Giuseppe, De Martino, Daniela, Esposito, Veronica, Galeone, Aldo, Navas, Luigi, Esposito, Silvia, Gargiulo, Sara, Fattet, Sarah, Donofrio, Vittoria, Cinalli, Giuseppe, Brunetti, Arturo, Vecchio, Luigi Del, Northcott, Paul A., Delattre, Olivier, Taylor, Michael D., Iolascon, Achille, Zollo, Massimo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656623/
https://www.ncbi.nlm.nih.gov/pubmed/19308264
http://dx.doi.org/10.1371/journal.pone.0004998

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