Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation

Obesity promotes insulin resistance and chronic inflammation. Disrupting any of several distinct steps in lipid synthesis decreases adiposity, but it is unclear if this approach coordinately corrects the environment that propagates metabolic disease. We tested the hypothesis that inactivation of FAS...

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Detalles Bibliográficos
Autores principales: Chakravarthy, Manu V., Zhu, Yimin, Yin, Li, Coleman, Trey, Pappan, Kirk L., Marshall, Connie A., McDaniel, Michael L., Semenkovich, Clay F.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656656/
https://www.ncbi.nlm.nih.gov/pubmed/19029118
http://dx.doi.org/10.1194/jlr.M800379-JLR200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656656/
https://www.ncbi.nlm.nih.gov/pubmed/19029118
http://dx.doi.org/10.1194/jlr.M800379-JLR200

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