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Allosteric Modulators of GABA(B) Receptors: Mechanism of Action and Therapeutic Perspective
γ-aminobutyric acid (GABA) plays important roles in the central nervous system, acting as a neurotransmitter on both ionotropic ligand-gated Cl(-)-channels, and metabotropic G-protein coupled receptors (GPCRs). These two types of receptors called GABA(A) (and C) and GABA(B) are the targets of major...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Bentham Science Publishers Ltd.
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656813/ https://www.ncbi.nlm.nih.gov/pubmed/19305802 http://dx.doi.org/10.2174/157015907781695919 |