Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells

INTRODUCTION: Basal-like carcinomas (BLCs) and human epidermal growth factor receptor 2 overexpressing (HER2+) carcinomas are the subgroups of breast cancers that have the most aggressive clinical behaviour. In contrast to HER2+ carcinomas, no targeted therapy is currently available for the treatmen...

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Detalles Bibliográficos
Autores principales: Marty, Bérengère, Maire, Virginie, Gravier, Eléonore, Rigaill, Guillem, Vincent-Salomon, Anne, Kappler, Marion, Lebigot, Ingrid, Djelti, Fathia, Tourdès, Audrey, Gestraud, Pierre, Hupé, Philippe, Barillot, Emmanuel, Cruzalegui, Francisco, Tucker, Gordon C, Stern, Marc-Henri, Thiery, Jean-Paul, Hickman, John A, Dubois, Thierry
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656897/
https://www.ncbi.nlm.nih.gov/pubmed/19055754
http://dx.doi.org/10.1186/bcr2204

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