Proteomic analysis of tumor necrosis factor-α resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype

INTRODUCTION: Despite intensive study of the mechanisms of chemotherapeutic drug resistance in human breast cancer, few reports have systematically investigated the mechanisms that underlie resistance to the chemotherapy-sensitizing agent tumor necrosis factor (TNF)-α. Additionally, the relationship...

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Detalles Bibliográficos
Autores principales: Zhou, Changhua, Nitschke, Ashley M, Xiong, Wei, Zhang, Qiang, Tang, Yan, Bloch, Michael, Elliott, Steven, Zhu, Yun, Bazzone, Lindsey, Yu, David, Weldon, Christopher B, Schiff, Rachel, McLachlan, John A, Beckman, Barbara S, Wiese, Thomas E, Nephew, Kenneth P, Shan, Bin, Burow, Matthew E, Wang, Guangdi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656902/
https://www.ncbi.nlm.nih.gov/pubmed/19087274
http://dx.doi.org/10.1186/bcr2210

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