Decreased ADP-Ribosyl Cyclase Activity in Peripheral Blood Mononuclear Cells from Diabetic Patients with Nephropathy

Aims/hypothesis. ADP-ribosyl-cyclase activity (ADPRCA) of CD38 and other ectoenzymes mainly generate cyclic adenosine 5’diphosphate-(ADP-) ribose (cADPR) as a second messenger in various mammalian cells, including pancreatic beta cells and peripheral blood mononuclear cells (PBMCs). Since PBMCs cont...

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Detalles Bibliográficos
Autores principales: Ohtsuji, Michio, Yagi, Kunimasa, Shintaku-Kubota, Miyuki, Kojima-Koba, Yukiko, Ito, Naoko, Sugihara, Masako, Yamaaki, Naoto, Chujo, Daisuke, Nohara, Atsushi, Takeda, Yoshiyu, Kobayashi, Junji, Yamagishi, Masakazu, Higashida, Haruhiro
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656910/
https://www.ncbi.nlm.nih.gov/pubmed/19300526
http://dx.doi.org/10.1155/2008/897508

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