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Insight into mechanism of oxidative DNA damage in angiomyolipomas from TSC patients
BACKGROUND: The tuberous sclerosis complex (TSC) is caused by defects in one of two tumor suppressor genes, TSC-1 or TSC-2. TSC-2 gene encodes tuberin, a protein involved in the pathogenesis of kidney tumors, both angiomyolipomas and renal cell carcinomas. Loss of heterozygosity at the 8-oxoG-DNA gl...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657104/ https://www.ncbi.nlm.nih.gov/pubmed/19265534 http://dx.doi.org/10.1186/1476-4598-8-13 |