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Inhibition of p38 MAP kinase pathway induces apoptosis and prevents Epstein Barr virus reactivation in Raji cells exposed to lytic cycle inducing compounds

BACKGROUND: EBV lytic cycle activators, such as phorbol esters, anti-immunoglobulin, transforming growth factor β (TGFβ), sodium butyrate, induce apoptosis in EBV-negative but not in EBV-positive Burkitt's lymphoma (BL) cells. To investigate the molecular mechanisms allowing EBV-infected cells...

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Detalles Bibliográficos
Autores principales: Matusali, Giulia, Arena, Giuseppe, De Leo, Alessandra, Di Renzo, Livia, Mattia, Elena
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657105/
https://www.ncbi.nlm.nih.gov/pubmed/19272151
http://dx.doi.org/10.1186/1476-4598-8-18