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Loss of the Transcriptional Repressor PAG-3/Gfi-1 Results in Enhanced Neurosecretion that is Dependent on the Dense-Core Vesicle Membrane Protein IDA-1/IA-2

It is generally accepted that neuroendocrine cells regulate dense core vesicle (DCV) biogenesis and cargo packaging in response to secretory demands, although the molecular mechanisms of this process are poorly understood. One factor that has previously been implicated in DCV regulation is IA-2, a c...

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Detalles Bibliográficos
Autores principales: Cai, Tao, Hirai, Hiroki, Fukushige, Tetsunari, Yu, Ping, Zhang, Guofeng, Notkins, Abner L., Krause, Michael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657203/
https://www.ncbi.nlm.nih.gov/pubmed/19343207
http://dx.doi.org/10.1371/journal.pgen.1000447