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Vaccine-induced Immunity Circumvented by Typical Mycobacterium tuberculosis Beijing Strains

The frequency of typical and atypical Beijing strains of Mycobacterium tuberculosis was determined in the Netherlands; Vietnam; and Hong Kong Special Administrative Region, People’s Republic of China. The strains’ associations with drug resistance, M. bovis BCG vaccination, and patient characteristi...

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Detalles Bibliográficos
Autores principales: Kremer, Kristin, van der Werf, Marieke J., Au, Betty K.Y., Anh, Dang D., Kam, Kai M., Rogier van Doorn, H., Borgdorff, Martien W., van Soolingen, Dick
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657620/
https://www.ncbi.nlm.nih.gov/pubmed/19193289
http://dx.doi.org/10.3201/eid1502.080795
Descripción
Sumario:The frequency of typical and atypical Beijing strains of Mycobacterium tuberculosis was determined in the Netherlands; Vietnam; and Hong Kong Special Administrative Region, People’s Republic of China. The strains’ associations with drug resistance, M. bovis BCG vaccination, and patient characteristics were assessed. BCG vaccination may have positively selected the prevalent typical Beijing strains.