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Indexing TNF-α gene expression using a gene-targeted reporter cell line
BACKGROUND: Current cell-based drug screening technologies utilize randomly integrated reporter genes to index transcriptional activity of an endogenous gene of interest. In this context, reporter expression is controlled by known genetic elements that may only partially capture gene regulation and...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657777/ https://www.ncbi.nlm.nih.gov/pubmed/19220876 http://dx.doi.org/10.1186/1741-7007-7-8 |