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Indexing TNF-α gene expression using a gene-targeted reporter cell line

BACKGROUND: Current cell-based drug screening technologies utilize randomly integrated reporter genes to index transcriptional activity of an endogenous gene of interest. In this context, reporter expression is controlled by known genetic elements that may only partially capture gene regulation and...

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Detalles Bibliográficos
Autores principales:	Yan, Ziying, Lei-Butters, Diana, Engelhardt, John F, Leno, Gregory H
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657777/ https://www.ncbi.nlm.nih.gov/pubmed/19220876 http://dx.doi.org/10.1186/1741-7007-7-8

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