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Exploring and dissecting genome-wide gene expression responses of Penicillium chrysogenum to phenylacetic acid consumption and penicillinG production
BACKGROUND: Since the discovery of the antibacterial activity of penicillin by Fleming 80 years ago, improvements of penicillin titer were essentially achieved by classical strain improvement through mutagenesis and screening. The recent sequencing of Penicillium chrysogenum strain Wisconsin1255-54...
Autores principales: | Harris, Diana M, van der Krogt, Zita A, Klaassen, Paul, Raamsdonk, Leonie M, Hage, Susanne, van den Berg, Marco A, Bovenberg, Roel AL, Pronk, Jack T, Daran, Jean-Marc |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657799/ https://www.ncbi.nlm.nih.gov/pubmed/19203396 http://dx.doi.org/10.1186/1471-2164-10-75 |
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