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Cysteine Redox Potential Determines Pro-Inflammatory IL-1β Levels

BACKGROUND: Cysteine (Cys) and its disulfide, cystine (CySS) represent the major extracellular thiol/disulfide redox control system. The redox potential (E(h)) of Cys/CySS is centered at approximately −80 mV in the plasma of healthy adults, and oxidation of E(h) Cys/CySS is implicated in inflammatio...

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Detalles Bibliográficos
Autores principales: Iyer, Smita S., Accardi, Carolyn J., Ziegler, Thomas R., Blanco, Roberto A., Ritzenthaler, Jeffrey D., Rojas, Mauricio, Roman, Jesse, Jones, Dean P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657829/
https://www.ncbi.nlm.nih.gov/pubmed/19325908
http://dx.doi.org/10.1371/journal.pone.0005017