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Role of sgcR3 in positive regulation of enediyne antibiotic C-1027 production of Streptomyces globisporus C-1027

BACKGROUND: C-1027, produced by Streptomyces globisporus C-1027, is one of the most potent antitumoral agents. The biosynthetic gene cluster of C-1027, previously cloned and sequenced, contains at least three putative regulatory genes, i.e. sgcR1, sgcR2 and sgcR3. The predicted gene products of thes...

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Detalles Bibliográficos
Autores principales:	Wang, Lifei, Hu, Yunfeng, Zhang, Yanjuan, Wang, Songmei, Cui, Zhihui, Bao, Yi, Jiang, Wei, Hong, Bin
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657911/ https://www.ncbi.nlm.nih.gov/pubmed/19159491 http://dx.doi.org/10.1186/1471-2180-9-14

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