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The impact of analytic method on interpretation of outcomes in longitudinal clinical trials

AIMS: Various analytical strategies for addressing missing data in clinical trials are utilised in reporting study results. The most commonly used analytical methods include the last observation carried forward (LOCF), observed case (OC) and the mixed model for repeated measures (MMRM). Each method...

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Detalles Bibliográficos
Autores principales: Prakash, A, Risser, R C, Mallinckrodt, C H
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658028/
https://www.ncbi.nlm.nih.gov/pubmed/18564199
http://dx.doi.org/10.1111/j.1742-1241.2008.01808.x