Cargando…

The impact of analytic method on interpretation of outcomes in longitudinal clinical trials

AIMS: Various analytical strategies for addressing missing data in clinical trials are utilised in reporting study results. The most commonly used analytical methods include the last observation carried forward (LOCF), observed case (OC) and the mixed model for repeated measures (MMRM). Each method...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prakash, A, Risser, R C, Mallinckrodt, C H
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2008
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658028/ https://www.ncbi.nlm.nih.gov/pubmed/18564199 http://dx.doi.org/10.1111/j.1742-1241.2008.01808.x

Ejemplares similares

lgpr: an interpretable non-parametric method for inferring covariate effects from longitudinal data
por: Timonen, Juho, et al.
Publicado: (2021)

Measurement of Symptom Change Following Web-Based Psychotherapy: Statistical Characteristics and Analytical Methods for Measuring and Interpreting Change
por: Karin, Eyal, et al.
Publicado: (2018)

The Impact of Medical Interpretation Method on Time and Errors
por: Gany, Francesca, et al.
Publicado: (2007)

Measuring change in health-related quality of life: the impact of different analytical methods on the interpretation of treatment effects in glioma patients
por: Coomans, Marijke B, et al.
Publicado: (2020)

Evaluating dose response from flexible dose clinical trials
por: Lipkovich, Ilya, et al.
Publicado: (2008)

A Framework for Modeling and Interpreting Patient Subgroups Applied to Hospital Readmission: Visual Analytical Approach
por: Bhavnani, Suresh K, et al.
Publicado: (2022)

Clinical Impact of an Analytic Tool for Predicting the Fall Risk in Inpatients: Controlled Interrupted Time Series
por: Cho, Insook, et al.
Publicado: (2021)

Characterization of analytical errors in thromboelastography interpretation
por: Mukhopadhyay, Tapasyapreeti, et al.
Publicado: (2020)

The efficacy of duloxetine: A comprehensive summary of results from MMRM and LOCF_ANCOVA in eight clinical trials
por: Mallinckrodt, Craig H, et al.
Publicado: (2004)

Interpreting the Outcomes of Automated Internet-Based Randomized Trials: Example of an International Smoking Cessation Study
por: Leykin, Yan, et al.
Publicado: (2012)

Systematic review of analytical methods applied to longitudinal studies of malaria
por: Stanley, Christopher C., et al.
Publicado: (2019)

Definition, reporting, and interpretation of composite outcomes in clinical trials: systematic review
por: Cordoba, Gloria, et al.
Publicado: (2010)

Interpreting patient-reported outcomes from clinical trials in COPD: a discussion
por: Jones, Paul W, et al.
Publicado: (2016)

Interactive Visual Displays for Interpreting the Results of Clinical Trials: Formative Evaluation With Case Vignettes
por: Bian, Jiantao, et al.
Publicado: (2018)

Verification of quantitative analytical methods in medical laboratories
por: Abdel Ghafar, Muhammad T., et al.
Publicado: (2021)

Patient Satisfaction with Different Interpreting Methods: A Randomized Controlled Trial
por: Gany, Francesca, et al.
Publicado: (2007)

Simulation study comparing analytical methods for single-item longitudinal patient-reported outcomes data
por: Calsavara, Vinicius F., et al.
Publicado: (2022)

Pioglitazone: A review of analytical methods
por: Satheeshkumar, N., et al.
Publicado: (2014)

Combined analytical approach empowers precise spectroscopic interpretation of subcellular components of pancreatic cancer cells
por: Szymoński, Krzysztof, et al.
Publicado: (2023)

Novel analytical methods to interpret large sequencing data from small sample sizes
por: Lichou, Florence, et al.
Publicado: (2019)

Interpretable Trials: Is Interpretability a Reason Why Clinical Trials Fail?
por: Chao, Yi-Sheng, et al.
Publicado: (2021)

The Impact of Bioinformatics Pipelines on Microbiota Studies: Does the Analytical “Microscope” Affect the Biological Interpretation?
por: Siegwald, Léa, et al.
Publicado: (2019)

Visual analytics tool for the interpretation of hidden states in recurrent neural networks
por: Garcia, Rafael, et al.
Publicado: (2021)

Improvements to the interpretation of longitudinal bunch profiles
por: Lauckner, R J, et al.
Publicado: (1991)

Bayesian methods for the design and interpretation of clinical trials in very rare diseases
por: Hampson, Lisa V, et al.
Publicado: (2014)

Re-evaluating randomized clinical trials of psychological interventions: Impact of response shift on the interpretation of trial results
por: Verdam, M. G. E., et al.
Publicado: (2021)

Bayesian Hierarchical Methods to Interpret the (13)C-Octanoic Acid Breath Test for Gastric Emptying
por: Bluck, Leslie J.C., et al.
Publicado: (2010)

Incorporating historical controls in clinical trials with longitudinal outcomes using the modified power prior
por: Qi, Hongchao, et al.
Publicado: (2022)

Interpreting the results of patient reported outcome measures in clinical trials: The clinician's perspective
por: Schünemann, Holger J, et al.
Publicado: (2006)

Interpreting regression models in clinical outcome studies
por: Hamilton, D. F., et al.
Publicado: (2015)

A Visual Analytic Tool (VIADS) to Assist the Hypothesis Generation Process in Clinical Research: Mixed Methods Usability Study
por: Jing, Xia, et al.
Publicado: (2023)

The Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD (IMPACT-AD): A Novel Clinical Trials Training Program
por: Berkness, Tyler, et al.
Publicado: (2021)

Permanent Deformation of the LHC Collimator Jaws Induced by Shock Beam Impact: an Analytical and Numerical Interpretation
por: Bertarelli, Alessandro, et al.
Publicado: (2006)

Improving the Clinical Interpretation of Transcutaneous Carbon Dioxide and Oxygen Measurements in the Neonatal Intensive Care Unit
por: van Essen, Tanja, et al.
Publicado: (2023)

Interpretation of time-to-event outcomes in randomized trials: an online randomized experiment
por: Weir, I R, et al.
Publicado: (2019)

Expectation pooling: an effective and interpretable pooling method for predicting DNA–protein binding
por: Luo, Xiao, et al.
Publicado: (2020)

An analytical approach to evaluate the impact of age demographics in a pandemic
por: Abdulrashid, Ismail, et al.
Publicado: (2023)

Meta-analysis as Statistical and Analytical Method of Journal’s Content Scientific Evaluation
por: Masic, Izet, et al.
Publicado: (2015)

The Evaluation of Analytical Performance of Immunoassay Tests by using Six-sigma Method
por: Nar, Rukiye, et al.
Publicado: (2017)

Readability Analysis of the Package Leaflets for Biological Medicines Available on the Internet Between 2007 and 2013: An Analytical Longitudinal Study
por: Piñero-López, María Ángeles, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_hm5t3hsu8b074nk4uobkiqmflr