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Cyclical Chromatin Looping and Transcription Factor Association on the Regulatory Regions of the p21 (CDKN1A) Gene in Response to 1α,25-Dihydroxyvitamin D(3)

The nuclear receptor vitamin D receptor (VDR) is known to associate with three vitamin D response element (VDREs)-containing regions within the CDKN1A (p21) gene region. Here we show in MDA-MB453 breast cancer cells that the natural VDR ligand 1α,25-dihydroxyvitamin D(3) causes cyclical transcriptio...

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Detalles Bibliográficos
Autores principales:	Saramäki, Anna, Diermeier, Sarah, Kellner, Ruth, Laitinen, Heidi, Vaïsänen, Sami, Carlberg, Carsten
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2009
Materias:	Transcription, Chromatin, and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658101/ https://www.ncbi.nlm.nih.gov/pubmed/19122196 http://dx.doi.org/10.1074/jbc.M808090200

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