Cargando…
Breast cancer incidence, stage, treatment and survival in ethnic groups in South East England
Studies from the US have shown variations in breast cancer incidence, stage distribution, treatment and survival between ethnic groups. Data on 35 631 women diagnosed with breast cancer in South East England between 1998 and 2003 with self-assigned ethnicity information available were analysed. Resu...
Autores principales: | , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658548/ https://www.ncbi.nlm.nih.gov/pubmed/19127253 http://dx.doi.org/10.1038/sj.bjc.6604852 |
_version_ | 1782165641431613440 |
---|---|
author | Jack, R H Davies, E A Møller, H |
author_facet | Jack, R H Davies, E A Møller, H |
author_sort | Jack, R H |
collection | PubMed |
description | Studies from the US have shown variations in breast cancer incidence, stage distribution, treatment and survival between ethnic groups. Data on 35 631 women diagnosed with breast cancer in South East England between 1998 and 2003 with self-assigned ethnicity information available were analysed. Results are reported for White, Indian, Pakistani, Bangladeshi, Black Caribbean, Black African and Chinese women. Age-standardised breast cancer incidence rate ratios, patterns of stage of disease at diagnosis, treatment, overall and breast cancer-specific survival were examined. All ethnic groups studied had lower age-standardised breast cancer incidence rates than White women, with Bangladeshi women having the lowest rate ratio (0.23, 95% CI: 0.20–0.26). White women were the most likely to have a stage recorded at diagnosis (adjusted proportion 75%), and least likely to be diagnosed with metastatic disease (7%). Black African women were the least likely to have a record of cancer surgery (63%) or hormone therapy (32%), and most likely to receive chemotherapy (38%). After fully adjusting for age, socioeconomic deprivation, stage of disease and treatment received, there was no significant variation in breast cancer-specific survival. However, Black African women had significantly worse overall survival (hazard ratio 1.24, P=0.025). These findings suggest that a strategy of earlier detection should be pursued in Black and South Asian women. |
format | Text |
id | pubmed-2658548 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-26585482010-02-10 Breast cancer incidence, stage, treatment and survival in ethnic groups in South East England Jack, R H Davies, E A Møller, H Br J Cancer Epidemiology Studies from the US have shown variations in breast cancer incidence, stage distribution, treatment and survival between ethnic groups. Data on 35 631 women diagnosed with breast cancer in South East England between 1998 and 2003 with self-assigned ethnicity information available were analysed. Results are reported for White, Indian, Pakistani, Bangladeshi, Black Caribbean, Black African and Chinese women. Age-standardised breast cancer incidence rate ratios, patterns of stage of disease at diagnosis, treatment, overall and breast cancer-specific survival were examined. All ethnic groups studied had lower age-standardised breast cancer incidence rates than White women, with Bangladeshi women having the lowest rate ratio (0.23, 95% CI: 0.20–0.26). White women were the most likely to have a stage recorded at diagnosis (adjusted proportion 75%), and least likely to be diagnosed with metastatic disease (7%). Black African women were the least likely to have a record of cancer surgery (63%) or hormone therapy (32%), and most likely to receive chemotherapy (38%). After fully adjusting for age, socioeconomic deprivation, stage of disease and treatment received, there was no significant variation in breast cancer-specific survival. However, Black African women had significantly worse overall survival (hazard ratio 1.24, P=0.025). These findings suggest that a strategy of earlier detection should be pursued in Black and South Asian women. Nature Publishing Group 2009-02-10 2009-01-06 /pmc/articles/PMC2658548/ /pubmed/19127253 http://dx.doi.org/10.1038/sj.bjc.6604852 Text en Copyright © 2009 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Epidemiology Jack, R H Davies, E A Møller, H Breast cancer incidence, stage, treatment and survival in ethnic groups in South East England |
title | Breast cancer incidence, stage, treatment and survival in ethnic groups in South East England |
title_full | Breast cancer incidence, stage, treatment and survival in ethnic groups in South East England |
title_fullStr | Breast cancer incidence, stage, treatment and survival in ethnic groups in South East England |
title_full_unstemmed | Breast cancer incidence, stage, treatment and survival in ethnic groups in South East England |
title_short | Breast cancer incidence, stage, treatment and survival in ethnic groups in South East England |
title_sort | breast cancer incidence, stage, treatment and survival in ethnic groups in south east england |
topic | Epidemiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658548/ https://www.ncbi.nlm.nih.gov/pubmed/19127253 http://dx.doi.org/10.1038/sj.bjc.6604852 |
work_keys_str_mv | AT jackrh breastcancerincidencestagetreatmentandsurvivalinethnicgroupsinsoutheastengland AT daviesea breastcancerincidencestagetreatmentandsurvivalinethnicgroupsinsoutheastengland AT møllerh breastcancerincidencestagetreatmentandsurvivalinethnicgroupsinsoutheastengland |