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Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation

It has been proposed that inhibitors of an oncogene's effects on multipotent hematopoietic progenitor cell differentiation may change the properties of the leukemic stem cells and complement the clinical use of cytotoxic drugs. Using zebrafish, we developed a robust in vivo hematopoietic differ...

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Detalles Bibliográficos
Autores principales: Yeh, Jing-Ruey J., Munson, Kathleen M., Elagib, Kamaleldin E., Goldfarb, Adam N., Sweetser, David A., Peterson, Randall T.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658727/
https://www.ncbi.nlm.nih.gov/pubmed/19172146
http://dx.doi.org/10.1038/nchembio.147