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Influence of parasite encoded inhibitors of serine peptidases in early infection of macrophages with Leishmania major
Ecotin is a potent inhibitor of family S1A serine peptidases, enzymes lacking in the protozoan parasite Leishmania major. Nevertheless, L. major has three ecotin-like genes, termed inhibitor of serine peptidase (ISP). ISP1 is expressed in vector-borne procyclic and metacyclic promastigotes, whereas...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659362/ https://www.ncbi.nlm.nih.gov/pubmed/19016791 http://dx.doi.org/10.1111/j.1462-5822.2008.01243.x |