Cargando…

Influence of parasite encoded inhibitors of serine peptidases in early infection of macrophages with Leishmania major

Ecotin is a potent inhibitor of family S1A serine peptidases, enzymes lacking in the protozoan parasite Leishmania major. Nevertheless, L. major has three ecotin-like genes, termed inhibitor of serine peptidase (ISP). ISP1 is expressed in vector-borne procyclic and metacyclic promastigotes, whereas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Eschenlauer, Sylvain C P, Faria, Marilia S, Morrison, Lesley S, Bland, Nicolas, Ribeiro-Gomes, Flavia L, DosReis, George A, Coombs, Graham H, Lima, Ana Paula C A, Mottram, Jeremy C
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2009
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659362/ https://www.ncbi.nlm.nih.gov/pubmed/19016791 http://dx.doi.org/10.1111/j.1462-5822.2008.01243.x

Ejemplares similares

Ecotin-like serine peptidase inhibitor ISP1 of Leishmania major plays a role in flagellar pocket dynamics and promastigote differentiation
por: Morrison, Lesley S, et al.
Publicado: (2012)

Distinct Roles in Autophagy and Importance in Infectivity of the Two ATG4 Cysteine Peptidases of Leishmania major
por: Williams, Roderick A. M., et al.
Publicado: (2013)

Inhibitor of serine peptidase 2 enhances Leishmania major survival in the skin through control of monocytes and monocyte-derived cells
por: Goundry, Amy, et al.
Publicado: (2018)

Studies on the CPA cysteine peptidase in the Leishmania infantum genome strain JPCM5
por: Denise, Hubert, et al.
Publicado: (2006)

An Essential Signal Peptide Peptidase Identified in an RNAi Screen of Serine Peptidases of Trypanosoma brucei
por: Moss, Catherine X., et al.
Publicado: (2015)

Role of inhibitors of serine peptidases in protecting Leishmania donovani against the hydrolytic peptidases of sand fly midgut
por: Verma, Sudha, et al.
Publicado: (2017)

Role of the inhibitor of serine peptidase 2 (ISP2) of Trypanosoma brucei rhodesiense in parasite virulence and modulation of the inflammatory responses of the host
por: Levy, David Jessula, et al.
Publicado: (2021)

The role of conserved residues of chagasin in the inhibition of cysteine peptidases
por: dos Reis, Flavia C.G., et al.
Publicado: (2008)

Retraction Note: Role of inhibitors of serine peptidases in protecting Leishmania donovani against the hydrolytic peptidases of sand fly midgut
por: Verma, Sudha, et al.
Publicado: (2023)

The SNARE protein family of Leishmania major
por: Besteiro, Sébastien, et al.
Publicado: (2006)

Toll-Like Receptors in Leishmania Infections: Guardians or Promoters?
por: Faria, Marilia S., et al.
Publicado: (2012)

Sugarcane Serine Peptidase Inhibitors, Serine Peptidases, and Clp Protease System Subunits Associated with Sugarcane Borer (Diatraea saccharalis) Herbivory and Wounding
por: Medeiros, Ane H., et al.
Publicado: (2016)

Cysteine Peptidase B Regulates Leishmania mexicana Virulence through the Modulation of GP63 Expression
por: Casgrain, Pierre-André, et al.
Publicado: (2016)

Protein turnover and differentiation in Leishmania
por: Besteiro, Sébastien, et al.
Publicado: (2007)

[2] Families of serine peptidases
por: Rawlings, Neil D., et al.
Publicado: (1994)

Campylobacter jejuni gene cj0511 encodes a serine peptidase essential for colonisation
por: Karlyshev, A.V., et al.
Publicado: (2014)

Role of the Trypanosoma brucei natural cysteine peptidase inhibitor ICP in differentiation and virulence
por: Santos, Camila C, et al.
Publicado: (2007)

Leishmania donovani Inhibitor of Serine Peptidases 2 Mediated Inhibition of Lectin Pathway and Upregulation of C5aR Signaling Promote Parasite Survival inside Host
por: Verma, Sudha, et al.
Publicado: (2018)

Adaptation of Helicoverpa armigera to Soybean Peptidase Inhibitors Is Associated with the Transgenerational Upregulation of Serine Peptidases
por: Velasquez-Vasconez, Pedro A., et al.
Publicado: (2022)

SAM domain-dependent activity of PfTKL3, an essential tyrosine kinase-like kinase of the human malaria parasite Plasmodiumfalciparum
por: Abdi, Abdirahman, et al.
Publicado: (2010)

Leishmania mexicana metacaspase is a negative regulator of amastigote proliferation in mammalian cells
por: Castanys-Muñoz, E, et al.
Publicado: (2012)

Candidates for Balancing Selection in Leishmania donovani Complex Parasites
por: Grace, Cooper Alastair, et al.
Publicado: (2021)

The Comparative Genomics and Phylogenomics of Leishmania amazonensis Parasite
por: Tschoeke, Diogo A, et al.
Publicado: (2014)

Innate Immunity to Leishmania Infection: Within Phagocytes
por: Lopes, Marcela Freitas, et al.
Publicado: (2014)

All-Trans Retinoic Acid Promotes an M1- to M2-Phenotype Shift and Inhibits Macrophage-Mediated Immunity to Leishmania major
por: Vellozo, Natália S., et al.
Publicado: (2017)

Tissue Specific Dual RNA-Seq Defines Host–Parasite Interplay in Murine Visceral Leishmaniasis Caused by Leishmania donovani and Leishmania infantum
por: Forrester, Sarah, et al.
Publicado: (2022)

Crystal Structure and Activity Studies of the C11 Cysteine Peptidase from Parabacteroides merdae in the Human Gut Microbiome
por: McLuskey, Karen, et al.
Publicado: (2016)

17-AAG-Induced Activation of the Autophagic Pathway in Leishmania Is Associated with Parasite Death
por: Petersen, Antonio Luis de O. A., et al.
Publicado: (2021)

Neutrophil elastase promotes Leishmania donovani infection via interferon-β
por: Dias, Bruna T., et al.
Publicado: (2019)

Infection with Leishmania major Induces a Cellular Stress Response in Macrophages
por: Filardy, Alessandra A., et al.
Publicado: (2014)

ATG5 Is Essential for ATG8-Dependent Autophagy and Mitochondrial Homeostasis in Leishmania major
por: Williams, Roderick A. M., et al.
Publicado: (2012)

Role of protein kinase R in the killing of Leishmania major by macrophages in response to neutrophil elastase and TLR4 via TNFα and IFNβ
por: Faria, Marilia S., et al.
Publicado: (2014)

Comparative structural analysis of the caspase family with other clan CD cysteine peptidases
por: McLuskey, Karen, et al.
Publicado: (2015)

Crystal Structure of Leishmania major Oligopeptidase B Gives Insight into the Enzymatic Properties of a Trypanosomatid Virulence Factor
por: McLuskey, Karen, et al.
Publicado: (2010)

Identification of Semicarbazones, Thiosemicarbazones and Triazine Nitriles as Inhibitors of Leishmania mexicana Cysteine Protease CPB
por: Schröder, Jörg, et al.
Publicado: (2013)

Leishmania infantum Asparagine Synthetase A Is Dispensable for Parasites Survival and Infectivity
por: Faria, Joana, et al.
Publicado: (2016)

Glycosome turnover in Leishmania major is mediated by autophagy
por: Cull, Benjamin, et al.
Publicado: (2015)

Interactions of “Bora-Penicilloates” with Serine β-Lactamases and DD-Peptidases
por: Dzhekieva, Liudmila, et al.
Publicado: (2014)

Pestivirus NS2-3/NS3 Serine Peptidase
por: Tautz, Norbert, et al.
Publicado: (2013)

Serine Proteases of Parasitic Helminths
por: Yang, Yong, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_4qj32l0v4oauv5s5qg50aofmjn