Correlations between clinical and physiological consequences of the novel mutation R878C in a highly conserved pore residue in the cardiac Na(+) channel

AIM: We compared the clinical and physiological consequences of the novel mutation R878C in a highly conserved pore residue in domain II (S5-S6) of human, hNa(v)1.5, cardiac Na(+) channels. METHODS: Full clinical evaluation of pedigree members through three generations of a Chinese family combined w...

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Detalles Bibliográficos
Autores principales: Zhang, Y, Wang, T, Ma, A, Zhou, X, Gui, J, Wan, H, Shi, R, Huang, C, Grace, A A, Huang, C L-H, Trump, D, Zhang, H, Zimmer, T, Lei, M
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Cardiovascular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659387/
https://www.ncbi.nlm.nih.gov/pubmed/18616619
http://dx.doi.org/10.1111/j.1748-1716.2008.01883.x

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