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Pitfalls in the design and analysis of paediatric clinical trials: a case of a ‘failed’ multi-centre study, and potential solutions
Aim: To increase awareness of possible pitfalls in the design and analysis of a multi-centre randomized clinical trial and to give an overview of alternative study designs and their consequences for power analyses in case of limited availability of trial participants. Methods: Investigation of the a...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659390/ https://www.ncbi.nlm.nih.gov/pubmed/18826493 http://dx.doi.org/10.1111/j.1651-2227.2008.01048.x |