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Blockade of VEGFR2 and Not VEGFR1 Can Limit Diet-Induced Fat Tissue Expansion: Role of Local versus Bone Marrow-Derived Endothelial Cells

BACKGROUND: We investigated if new vessel formation in fat involves the contribution of local tissue-derived endothelial cells (i.e., angiogenesis) or bone marrow-derived cells (BMDCs, i.e. vasculogenesis) and if antiangiogenic treatment by blockade of vascular endothelial growth factor (VEGF) recep...

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Detalles Bibliográficos
Autores principales:	Tam, Joshua, Duda, Dan G., Perentes, Jean Y., Quadri, Rehan S., Fukumura, Dai, Jain, Rakesh K.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659427/ https://www.ncbi.nlm.nih.gov/pubmed/19333381 http://dx.doi.org/10.1371/journal.pone.0004974

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