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Su(z)2 Antagonizes Auto-Repression of Myc in Drosophila, Increasing Myc Levels and Subsequent Trans-Activation
All tumor cell lines that have been tested are defective for Myc auto-repression, and have high levels of Myc produced from wild type loci and re-arranged loci. Like mammalian Myc auto-repression, Myc protein represses the expression of its gene, dmyc, in Drosophila. This activity requires Polycomb...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659448/ https://www.ncbi.nlm.nih.gov/pubmed/19333393 http://dx.doi.org/10.1371/journal.pone.0005076 |