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Knottin cyclization: impact on structure and dynamics

BACKGROUND: Present in various species, the knottins (also referred to as inhibitor cystine knots) constitute a group of extremely stable miniproteins with a plethora of biological activities. Owing to their small size and their high stability, knottins are considered as excellent leads or scaffolds...

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Detalles Bibliográficos
Autores principales: Heitz, Annie, Avrutina, Olga, Le-Nguyen, Dung, Diederichsen, Ulf, Hernandez, Jean-François, Gracy, Jérôme, Kolmar, Harald, Chiche, Laurent
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659701/
https://www.ncbi.nlm.nih.gov/pubmed/19077275
http://dx.doi.org/10.1186/1472-6807-8-54