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Knottin cyclization: impact on structure and dynamics
BACKGROUND: Present in various species, the knottins (also referred to as inhibitor cystine knots) constitute a group of extremely stable miniproteins with a plethora of biological activities. Owing to their small size and their high stability, knottins are considered as excellent leads or scaffolds...
Autores principales: | Heitz, Annie, Avrutina, Olga, Le-Nguyen, Dung, Diederichsen, Ulf, Hernandez, Jean-François, Gracy, Jérôme, Kolmar, Harald, Chiche, Laurent |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659701/ https://www.ncbi.nlm.nih.gov/pubmed/19077275 http://dx.doi.org/10.1186/1472-6807-8-54 |
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