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Inefficient Quality Control of Thermosensitive Proteins on the Plasma Membrane
BACKGROUND: Misfolded proteins are generally recognised by cellular quality control machinery, which typically results in their ubiquitination and degradation. For soluble cytoplasmic proteins, degradation is mediated by the proteasome. Membrane proteins that fail to fold correctly are subject to ER...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659772/ https://www.ncbi.nlm.nih.gov/pubmed/19337370 http://dx.doi.org/10.1371/journal.pone.0005038 |