Synergism of Heat Shock Protein 90 and Histone Deacetylase Inhibitors in Synovial Sarcoma

Current systemic therapies have little curative benefit for synovial sarcoma. Histone deacetylase (HDAC) inhibitors and the heat shock protein 90 (Hsp90) inhibitor 17-AAG have recently been shown to inhibit synovial sarcoma in preclinical models. We tested combinations of 17-AAG with the HDAC inhibi...

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Detalles Bibliográficos
Autores principales: Nguyen, Anne, Su, Le, Campbell, Belinda, Poulin, Neal M., Nielsen, Torsten O.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659882/
https://www.ncbi.nlm.nih.gov/pubmed/19325926
http://dx.doi.org/10.1155/2009/794901

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