Molecular Electron Microscopy: State of the Art and Current Challenges

[Image: see text] The objective of molecular electron microscopy (EM) is to use electron microscopes to visualize the structure of biological molecules. This Review provides a brief overview of the methods used in molecular EM, their respective strengths and successes, and current developments that...

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Detalles Bibliográficos
Autores principales: Stahlberg, Henning, Walz, Thomas
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660199/
https://www.ncbi.nlm.nih.gov/pubmed/18484707
http://dx.doi.org/10.1021/cb800037d
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author Stahlberg, Henning
Walz, Thomas
author_facet Stahlberg, Henning
Walz, Thomas
author_sort Stahlberg, Henning
collection PubMed
description [Image: see text] The objective of molecular electron microscopy (EM) is to use electron microscopes to visualize the structure of biological molecules. This Review provides a brief overview of the methods used in molecular EM, their respective strengths and successes, and current developments that promise an even more exciting future for molecular EM in the structural investigation of proteins and macromolecular complexes, studied in isolation or in the context of cells and tissues.
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spelling pubmed-26601992009-03-25 Molecular Electron Microscopy: State of the Art and Current Challenges Stahlberg, Henning Walz, Thomas ACS Chem Biol [Image: see text] The objective of molecular electron microscopy (EM) is to use electron microscopes to visualize the structure of biological molecules. This Review provides a brief overview of the methods used in molecular EM, their respective strengths and successes, and current developments that promise an even more exciting future for molecular EM in the structural investigation of proteins and macromolecular complexes, studied in isolation or in the context of cells and tissues. American Chemical Society 2008-05-16 2008-05-16 /pmc/articles/PMC2660199/ /pubmed/18484707 http://dx.doi.org/10.1021/cb800037d Text en Copyright © 2008 American Chemical Society http://pubs.acs.org This is an open-access article distributed under the ACS AuthorChoice Terms & Conditions. Any use of this article, must conform to the terms of that license which are available at http://pubs.acs.org.
spellingShingle Stahlberg, Henning
Walz, Thomas
Molecular Electron Microscopy: State of the Art and Current Challenges
title Molecular Electron Microscopy: State of the Art and Current Challenges
title_full Molecular Electron Microscopy: State of the Art and Current Challenges
title_fullStr Molecular Electron Microscopy: State of the Art and Current Challenges
title_full_unstemmed Molecular Electron Microscopy: State of the Art and Current Challenges
title_short Molecular Electron Microscopy: State of the Art and Current Challenges
title_sort molecular electron microscopy: state of the art and current challenges
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660199/
https://www.ncbi.nlm.nih.gov/pubmed/18484707
http://dx.doi.org/10.1021/cb800037d
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AT walzthomas molecularelectronmicroscopystateoftheartandcurrentchallenges

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