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Cellular localization of mitochondria contributes to K(v) channel-mediated regulation of cellular excitability in pulmonary but not mesenteric circulation

Mitochondria are proposed to be a major oxygen sensor in hypoxic pulmonary vasoconstriction (HPV), a unique response of the pulmonary circulation to low oxygen tension. Mitochondrial factors including reactive oxygen species, cytochrome c, ATP, and magnesium are potent modulators of voltage-gated K(...

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Detalles Bibliográficos
Autores principales: Firth, Amy L., Gordienko, Dmitri V., Yuill, Kathryn H., Smirnov, Sergey V.
Formato: Texto
Lenguaje:English
Publicado: American Physiological Society 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660209/
https://www.ncbi.nlm.nih.gov/pubmed/19098127
http://dx.doi.org/10.1152/ajplung.90341.2008