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Cellular localization of mitochondria contributes to K(v) channel-mediated regulation of cellular excitability in pulmonary but not mesenteric circulation
Mitochondria are proposed to be a major oxygen sensor in hypoxic pulmonary vasoconstriction (HPV), a unique response of the pulmonary circulation to low oxygen tension. Mitochondrial factors including reactive oxygen species, cytochrome c, ATP, and magnesium are potent modulators of voltage-gated K(...
Autores principales: | Firth, Amy L., Gordienko, Dmitri V., Yuill, Kathryn H., Smirnov, Sergey V. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660209/ https://www.ncbi.nlm.nih.gov/pubmed/19098127 http://dx.doi.org/10.1152/ajplung.90341.2008 |
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