Transgenic up-regulation of alpha-CaMKII in forebrain leads to increased anxiety-like behaviors and aggression

BACKGROUND: Previous studies have demonstrated essential roles for alpha-calcium/calmodulin-dependent protein kinase II (alpha-CaMKII) in learning, memory and long-term potentiation (LTP). However, previous studies have also shown that alpha-CaMKII (+/-) heterozygous knockout mice display a dramatic...

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Detalles Bibliográficos
Autores principales: Hasegawa, Shunsuke, Furuichi, Takahiro, Yoshida, Taro, Endoh, Kengo, Kato, Kenichi, Sado, Megumi, Maeda, Ryouta, Kitamoto, Aya, Miyao, Takahisa, Suzuki, Ryosuke, Homma, Seiichi, Masushige, Shoichi, Kajii, Yasushi, Kida, Satoshi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660323/
https://www.ncbi.nlm.nih.gov/pubmed/19257910
http://dx.doi.org/10.1186/1756-6606-2-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660323/
https://www.ncbi.nlm.nih.gov/pubmed/19257910
http://dx.doi.org/10.1186/1756-6606-2-6

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