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Transgenic up-regulation of alpha-CaMKII in forebrain leads to increased anxiety-like behaviors and aggression
BACKGROUND: Previous studies have demonstrated essential roles for alpha-calcium/calmodulin-dependent protein kinase II (alpha-CaMKII) in learning, memory and long-term potentiation (LTP). However, previous studies have also shown that alpha-CaMKII (+/-) heterozygous knockout mice display a dramatic...
Autores principales: | Hasegawa, Shunsuke, Furuichi, Takahiro, Yoshida, Taro, Endoh, Kengo, Kato, Kenichi, Sado, Megumi, Maeda, Ryouta, Kitamoto, Aya, Miyao, Takahisa, Suzuki, Ryosuke, Homma, Seiichi, Masushige, Shoichi, Kajii, Yasushi, Kida, Satoshi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660323/ https://www.ncbi.nlm.nih.gov/pubmed/19257910 http://dx.doi.org/10.1186/1756-6606-2-6 |
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