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FE65 Binds Teashirt, Inhibiting Expression of the Primate-Specific Caspase-4

The Alzheimer disease (AD) amyloid protein precursor (APP) can bind the FE65 adaptor protein and this complex can regulate gene expression. We carried out yeast two-hybrid studies with a PTB domain of FE65, focusing on those genes that might be involved in nuclear signaling, and identified and valid...

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Detalles Bibliográficos
Autores principales: Kajiwara, Yuji, Akram, Afia, Katsel, Pavel, Haroutunian, Vahram, Schmeidler, James, Beecham, Gary, Haines, Jonathan L., Pericak-Vance, Margaret A., Buxbaum, Joseph D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660419/
https://www.ncbi.nlm.nih.gov/pubmed/19343227
http://dx.doi.org/10.1371/journal.pone.0005071